中文名稱 核轉錄因子重組兔單克隆抗體
別 名 sex determining region Y box 1; SOX1_HUMAN; SRY; SOX-1; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1.
研究領域 發育生物學 神經生物學 干細胞 轉錄調節因子 表觀遺傳學
抗體來源 Rabbit
克隆類型 Monoclonal
克 隆 號 23C9
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 WB=1:500-1000 IP=1:20-100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
細胞定位 細胞核
性 狀 Liquid
濃 度 1mg/ml
免 疫 原 Recombinant human SOX1 protein (100-200aa):
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
產品介紹 Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
Function:
Transcriptional activator.
Subcellular Location:
Nucleus.
Tissue Specificity:
Mainly expressed in the developing central nervous system.
Post-translational modifications:
Sumoylation inhibits the transcriptional activity.
Similarity:
Contains 1 HMG box DNA-binding domain.
SWISS:
O00570
Gene ID:
6656
Database links:
Entrez Gene: 6656 HumanEntrez Gene: 20664 MouseOmim: 602148 HumanSwissProt: O00570 HumanSwissProt: P53783 MouseUnigene: 202526 HumanUnigene: 39088 Mouse
Important Note:
This product as su
我要詢價
*聯系方式：
(可以是QQ、MSN、電子郵箱、電話等，您的聯系方式不會被公開)
*內容：
