Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- RRID
- AB_2565682 (BioLegend Cat. No. 391405) AB_2565683 (BioLegend Cat. No. 391406)
Antigen Details
- Structure
- G Protein-Coupled Receptor super family
- Distribution
- Monocytes, B cells, T cells, and mature dendritic cells.
- Function
- Regulates trafficking and activation of leukocytes.
- Ligand/Receptor
- CXCL12/SDF-1 and CXCL11/I-TAC.
- Cell Type
- Monocytes, B cells, T cells, Dendritic cells
- Biology Area
- Cell Biology, Immunology, Signal Transduction
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Torossian F, et al. 2014. Blood 123:191.
2. Walentowicz-Sadlecka M, et al. 2014. PLoS One 1:e84629.
3. Yates TJ, et al. 2013. Cancer 119:61.
4. Burns JM, et al. 2006. J. Exp. Med. 203:2201.
5. Infantino S, et al. 2006. J. Immunol. 176:2197. - Gene ID
- 57007 View all products for this Gene ID
- UniProt
- View information about CXCR7 on UniProt.org