Product Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant CD301 (extracellular domain)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
H037G3 antibody binding is divalent cation dependent.
- Product Citations
-
- RRID
- AB_11219398 (BioLegend Cat. No. 354701) AB_11218998 (BioLegend Cat. No. 354702)
Antigen Details
- Structure
- 40 kD type II transmembrane glycoprotein, consists of a 39 amino acid (aa) cytoplasmic region, a 21 aa transmembrane segment and a 256 aa extracellular domain (ECD) with one carbohydrate recognition domain (CRD) and a neck region
- Distribution
-
Immature myeloid dendritic cells, activated macrophages
- Function
- Cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, immune response
- Interaction
- Carbohydrate determinants, GP envelope glycoprotein on Marburg and Ebola viruses
- Ligand/Receptor
- Glycans containing terminal GalNAc moieties
- Cell Type
- Dendritic cells, Macrophages
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Van Vliet SJ, et al. 2006. Nat. Immunol. 7:1200.
2. Higashi N, et al. 2002. J. Biol. Chem. 277:20686.
3. Tsuiji M, et al. 2002. J. Biol. Chem. 277:28892.
4. Valladeau J, et al. 2001. J. Immunol. 167:5767.
5. Suzuki N, et al. 1996. J. Immunol. 156:128. - Gene ID
- 10462 View all products for this Gene ID
- UniProt
- View information about CD301 on UniProt.org
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