Purified anti-NGAL (Lipocalin-2) Antibody

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訂購熱線：021-34661276

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant human NGAL
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
IP - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Clone M0415B7 does not cross-react with mouse NGAL.
RRID: AB_2564180 (BioLegend Cat. No. 661902)

Structure: 193 amino acid monomer with a predicted molecular weight of approximately 22 kD.
Distribution: Secreted by epithelial cells, macrophages, neutrophils; increased levels have been observed in plasma, serum, and urine in various conditions, such as metastatic breast and colorectal cancer, acute kidney injury, pancreatitis and preeclampsia.
Function: Apoptosis, innate immunity, renal development.
Interaction: Disulfide-linked with MMP9.
Ligand/Receptor: SLC22A17 (24p3R)
Cell Type: Epithelial cells, Macrophages, Neutrophils
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References: 1. Iqbal N, et al. 2013. Expert Opin. Med Diagn. 7:209.
2. Singer E, et al. 2013. Acta. Physiol. (Oxf) 207:663.
3. Palazzuoli A, et al. 2012. Clin. Chim. Acta. 413:1832.
4. Flo TH, et al. 2004. Nature 432:917.
5. Goetz DH, et al. 2002. Mol. Cell. 10:1033.
6. Leung L, et al. 2012. PLoS One 7:e46677.
7. Kjeldsen L, et al. 1993. J. Biol. Chem. 268:10425.
Gene ID: 3934 View all products for this Gene ID
UniProt: View information about NGAL on UniProt.org