Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
ELISA Detection - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by ELISA assay. For ELISA Detection applications, a concentration range of 0.5 - 4.0 ?g/mL is recommended. To obtain a linear standard curve, serial dilutions of IGFALS recombinant protein ranging from 3.125 to 100 ng/mL is recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
The biotinylated M6001E07 antibody is useful as the detection antibody in a sandwich ELISA assay, when used in conjunction with the purified M6005C04 antibody (Cat. No. 537302) as the capture antibody and Recombinant Human IGFALS (ELISA Std.) (Cat. No. 758809).
- Product Citations
-
- RRID
- AB_2783349 (BioLegend Cat. No. 537404)
Antigen Details
- Distribution
-
Produced by the liver and is mainly found in the postnatal serum.
- Function
- IGFALS production is stimulated by growth hormone and is important for extending the serum half life of IGF.
- Interaction
- IGF-1/IGF-2 and IGFBP-3/IGFBP-5 binary complexes
- Ligand/Receptor
- IGF-1/IGF-2 and IGFBP-3/IGFBP-5 binary complexes
- Biology Area
- Angiogenesis, Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Cell Cycle/DNA Replication, Cell Proliferation and Viability, Signal Transduction
- Molecular Family
- Carrier Proteins
- Antigen References
-
- Baxter RC, Dai J. 1994. Endocrinology. 134:848-852.
- Twigg SM, Baxter RC. 1998. J Biol Chem. 273(11):6074-9.
- Khosravi MJ, et al. 1997. J Clin Endocrinol Metab. 82:3944-3951.
- Domene HM, et al. 2004. New Eng J Med. 350:570-577.
- Domene HM, et al. 2005. J Endocrinol Invest. 28(5):43-6.
- Gene ID
- 3483 View all products for this Gene ID
- UniProt
- View information about IGFALS on UniProt.org
