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Purified anti-IGFALS (ALS) Antibody

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Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human IGFALS
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2566383 (BioLegend Cat. No. 680502)

Antigen Details

Structure
605 amino acids with a predicted molecular weight of 66 kD.
Distribution

Secreted protein.

Function
Serum protein bound to IGF to stabilize and assist its vascular localization and is involved in regulating homeostasis and actions of IGFs.
Interaction
IGF-I or IGF-II and IGFBP-3.
Biology Area
Cell Biology, Signal Transduction
Antigen References

1. Hogler W, et al. 2014. J. Clin. Endocrinol. Metab. 99:E703.
2. Domene HM, et al. 2007. J Clin. Endocrinol. Metab. 92:4444.
3. Domene HM, et al. 2009. Horm Res. 3:129.
4. Janosi JB, et al. 1999. J. Biol. Chem. 74:5992.
5. Janosi JB, et al. 1999. J. Biol. Chem. 274: 23328.
6. Boisclair YR, et al. 2001. J. Endocrinol. 170:63.
7. Haluzik M, et al. 2003. Diabetes. 52:2483.
8. Schreiner F, et al. 2013. Horm. Res. Poediatr. 80:24.

Gene ID
3483 View all products for this Gene ID
UniProt
View information about IGFALS on UniProt.org
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