| 產品編號 | bs-0369M-HRP |
| 英文名稱 | Mouse Anti-Rabbit IgM / HRP antibody |
| 中文名稱 | 辣根過氧化物酶標記的小鼠抗兔IgM |
| 別 名 | Mouse Anti-Rabbit IgM (HRP); Immunoglobulin M; |
 | Specific References (2) | bs-0369M-HRP has been referenced in 2 publications. [IF=2.35] Hou, Hong?Wei, et al. "Triptolide exerts protective effects against fibrosis following ileocolonic anastomosis by mechanisms involving the miR-16-1/HSP70 pathway in IL-10-deficient mice." International Journal of Molecular Medicine. WB ; Rabbit. [IF=1.922] Cao et al. Dickkopf?3 upregulation mediates the cardioprotective effects of curcumin on chronic heart failure. (2018) Mol.Med.Rep. 17:7249-7257 WB ; Rabbit. |
| 抗體來源 | Mouse |
| 克隆類型 | Polyclonal |
| 交叉反應 | Rabbit |
| 產品應用 | WB=1:1000-10000, IHC-P=1:100-500, IHC-F=1:100-1000, ELISA=1:1000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Liquid |
| 濃 度 | 2.0 mg/ml |
| 免 疫 原 | Native Rabbit IgM |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol. |
| 保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | Immunoglobulin M (IgM) normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
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