產品編號 | bs-0884P |
英文名稱 | Recombinant human IL-1Ra protein, His |
中文名稱 | 重組人白介素-1受體拮抗劑蛋白 |
別 名 | Recombinant Human Interleukin-1 receptor antagonist His Tag; Recombinant human IL-1Ra protein, His |
理論分子量 | 17kDa |
檢測分子量 | 20 kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 26-177/177 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內毒素 | Not analyzed |
表達系統 | E.coli |
活性 | Not tested |
標簽 | His |
緩 沖 液 | PBS (pH=7.4) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產品介紹 | IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. SWISS: P18510 Gene ID: 3557 ????L-lra-重組人白介素-1受體拮抗劑,通過與白細胞介素-1的Ⅰ型和Ⅱ型受體結合,特異性地阻斷白細胞介素-1的生物學作用。白介素1受體拮抗劑(IL-1Ra)是體內天然的一種對IL-1有拮抗作用的細胞因子。國際上對其的研究愈來愈受到重視。 重組人白介素1受體拮抗劑(rhIL-1Ra)作為一種生物制劑已經FDA批準應用于臨床治療細胞因子。 ????重組白介素1受體拮抗劑,分子量約17kD,純度大于98%。 |
產品圖片 | |
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