| 產品編號 | bs-49058P |
| 英文名稱 | Recombinant H5N6-NA protein, His |
| 中文名稱 | 重組H5N6-NA蛋白 |
| 別 名 | A0A240EUK5_9INFA; Neuraminidase · Influenza A virus (A/oriental magpie robin/HK/6154/2015(H5N6)); Neuraminidase; NA; GenBank: AOC37464.1; Recombinant H5N6-NA protein, His |
| 理論分子量 | 50kDa |
| 檢測分子量 | 55 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | IAV |
| 序 列 | 2-459/459 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內毒素 | Not analyzed |
| 表達系統 | E.coli |
| 活性 | Not tested |
| 標簽 | His |
| 緩 沖 液 | 20 mM Tris-HCl (pH=8.0) with 150 mM NaCl |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moities on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication. SWISS: A0A240EUK5 Gene ID: N/A |
| 產品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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