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重組人白細(xì)胞介素-17 (活性的)

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產(chǎn)品編號bs-48003P
英文名稱Recombinant human IL-17A protein (Active, HEK293)
中文名稱重組人白細(xì)胞介素-17 (活性的)
別    名rhIL-7; Interleukin-17; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL17A; IL-17A; Interleukin 17; Interleukin 17A; Interleukin17; Interleukin17A; Recombinant human IL-17A protein (Active, HEK293)  IL-17 重組蛋白; 白細(xì)胞介素-17; 重組人白細(xì)胞介素-17;
理論分子量16kDa
檢測分子量9-30 kDa
性    狀Lyophilized powder
濃    度>0.5 mg/ml
物    種Human
序    列20-155/155
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素<0.5 EU/μg as determined by LAL.
表達(dá)系統(tǒng)HEK293 cell
活性Yes
標(biāo)簽Tag free
緩 沖 液Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
保存條件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17(IL-17A) is a homodimer of two 136 amino acid chains that are secreted by activated T cells. IL-17A is expressed by activated Th17 cells. IL-17A induces stromal cells to produce proinflammatory and hematopoietic cytokines. It also enhances the surface expression of ICAM1 (intracellular adhesion molecule 1) in fibroblasts.

This recombinant human IL-17(IL-17A) is produced by human cells.

Biological activity:
The activity was measured by its ability to stimulate the proliferation of murine 2E8 cells.

Reconstitution:
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.



SWISS:
Q16552

Gene ID:
3605

產(chǎn)品圖片
The purity of the protein is greater than 95% as determined by reduced and non reduced SDS-PAGE
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