| 產品編號 | bs-48008P |
| 英文名稱 | Recombinant human IL-28A protein (Active, HEK293) |
| 中文名稱 | 重組人白介素28A (活性的, Tag free) |
| 別 名 | rhIL-28A; Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; rhIL-28A; EG330496; Ifnl2; IFNL2_HUMAN. ;Recombinant human IL-28A protein (Active, HEK293) 人白介素28A 重組蛋白; 人白細胞介素28A ; 重組人白介素28A; |
| 理論分子量 | 24kDa |
| 檢測分子量 | 17-38 kDa |
| 性 狀 | Lyophilized powder |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | Human |
| 序 列 | 26-200/200 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內毒素 | <0.5 EU/μg as determined by LAL. |
| 表達系統 | HEK293 cell |
| 活性 | Yes |
| 標簽 | Tag free |
| 緩 沖 液 | Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | IL-28A, also named interferon λ2 (IFNλ2), belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL-28A is induced by virus infection or double stranded RNA. IL-28A acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-28A has antiviral, antitumour and immunomodulatory activities, plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. This recombinant human IL-28A is produced by human cells.(Tag free) Biological activity: The activity was measured by its anti-virus function in A549 cells (human lung adenocarcinoma epithelial cell line) infected with encephalomyocarditis (EMC) virus. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: Q8IZJ0 Gene ID: 282616 |
| 產品圖片 |  The purity of the protein is greater than 95% as determined by reduced and non reduced SDS-PAGE |
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