| 產品編號 | bs-49102P |
| 英文名稱 | Recombinant HPV16 E6 protein, DsbC & His |
| 中文名稱 | 重組人類乳頭狀瘤病毒16-E6蛋白 |
| 別 名 | E6; HPV16 E6 protein; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16; Recombinant HPV16 E6 protein, DsbC & His |
| 理論分子量 | 49.5kDa |
| 檢測分子量 | 50 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | HPV |
| 序 列 | 1-158/158 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內毒素 | Not analyzed |
| 表達系統 | E.coli |
| 活性 | Not tested |
| 標簽 | DsbC & His |
| 緩 沖 液 | 20 mM Tris-HCl (pH=8.0) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. SWISS: P03126 Gene ID: 1489078 |
| 產品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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