產品編號 | bs-41229P |
英文名稱 | Recombinant human Pepsinogen C / PGC protein, His |
中文名稱 | 重組人胃蛋白酶原2蛋白 |
別 名 | PEPC_HUMAN; Gastricsin: PGC; Pepsinogen C; Progastricsin; Pepsinogen II; Pepsinogen-2; Pepsinogen2; Recombinant human Pepsinogen C / PGC protein, His |
理論分子量 | 40kDa |
檢測分子量 | 40 kDa |
性 狀 | Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 16-388/388 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內毒素 | Not analyzed |
表達系統 | E.coli |
活性 | Not tested |
標簽 | His |
緩 沖 液 | 20 mM Tris-HCl with 2 M Urea |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產品介紹 | This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq]. SWISS: P20142 Gene ID: 5225 |
產品圖片 | |
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