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重組人唾液酸結(jié)合性免疫球蛋白樣凝集素15

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產(chǎn)品編號(hào)bs-43036P
英文名稱Recombinant human SIGLEC15 protein, His (HEK293)
中文名稱重組人唾液酸結(jié)合性免疫球蛋白樣凝集素15
別    名CD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15; SIGLEC15; Recombinant human SIGLEC15 protein, His (HEK293)  
理論分子量30kDa
檢測(cè)分子量34 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Human
序    列20-263/328
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)HEK293 cell
活性Yes
標(biāo)簽His
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Two families of mammalian lectin-like adhesion molecules, the selectins and the sialoadhesins, bind glycoconjugate ligands in a sialic acid-dependent manner. The sialic acid-binding immunoglobulin superfamily lectins, designated Siglecs or sialoadhesins, recognize sialylated ligands and play a key role in mediating sialic-acid dependent binding to cells. Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.

SWISS:
Q6ZMC9

Gene ID:
284266

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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