| 產(chǎn)品編號(hào) | bs-41334P |
| 英文名稱 | Recombinant mouse ASC protein, His |
| 中文名稱 | 重組小鼠凋亡相關(guān)斑點(diǎn)樣蛋白ASC蛋白 |
| 別 名 | TMS1; Apoptosis associated speck like protein containing a CARD; Apoptosis-associated speck-like protein containing a CARD; ASC_HUMAN; CARD 5; CARD5; Caspase recruitment domain containing protein 5; Caspase recruitment domain protein 5; Caspase recruitment domain-containing protein 5; hASC; MGC10332; PYCARD; TMS-1; PYD and CARD domain containing; PYD and CARD domain containing protein; PYD and CARD domain-containing protein; Target of methylation induced silencing 1; Target of methylation-induced silencing 1; TMS 1; Recombinant mouse ASC protein, His |
| 理論分子量 | 15kDa |
| 檢測(cè)分子量 | 26 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | Mouse |
| 序 列 | 1-193/193 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | E.coli |
| 活性 | Not tested |
| 標(biāo)簽 | His |
| 緩 沖 液 | 20 mM Tris-HCl (pH=8.0) with 50 mM NaCl |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. Tissue specificity: Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell lines HL-60 and U937, but not in Jurkat T-cell lymphoma and Daudi Burkitt's lymphoma. SWISS: Q9EPB4 Gene ID: 66824 |
| 產(chǎn)品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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