| 產品編號 | bs-42114P |
| 英文名稱 | Recombinant human RIPK1 protein, N-His |
| 中文名稱 | 重組絲氨酸蘇氨酸激酶1受體相互作用蛋白 |
| 別 名 | Cell death protein RIP; Receptor (TNFRSF) interacting serine threonine kinase 1; Receptor interacting protein; Receptor interacting serine threonine protein kinase 1; Receptor TNFRSF interacting serine threonine kinase 1; Receptor-interacting protein 1; Receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; Rip-1; RIPK 1; RIPK-1; RIPK1_HUMAN; Serine threonine protein kinase RIP; Serine/threonine-protein kinase RIP. |
| 理論分子量 | 28.7kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >1mg/ml |
| 物 種 | Human |
| 純 度 | >90% as determined by SDS-PAGE |
| 內毒素 | Not analyzed |
| 表達系統 | E.coli |
| 活性 | Not tested |
| 標簽 | C-His |
| 緩 沖 液 | 20mM Tris (pH=8.0) with 8M Urea |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains. SWISS: Q13546 Gene ID: 8737 |
| 產品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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