產(chǎn)品編號(hào) | bs-42139P |
英文名稱 | Recombinant human GBP2 protein, N-His |
中文名稱 | 重組G蛋白結(jié)合蛋白2 |
別 名 | GBP 2; GBP2; GBP-2; GTP binding protein 2; Guanine nucleotide binding protein 2; Guanylate binding protein 2 interferon inducible; HuGBP 2; HuGBP2; GBP2_HUMAN. |
理論分子量 | 31.2kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >1mg/ml |
物 種 | Human |
序 列 | 50-306/591 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達(dá)系統(tǒng) | E.coli |
活性 | Not tested |
標(biāo)簽 | N-His |
緩 沖 液 | 20mM Tris (pH=8.0) with 8M Urea |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4). GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4). GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1). GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3). Specifically, GBP1 is expressed in cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS (5). SWISS: P32456 Gene ID: 2634 |
產(chǎn)品圖片 | |
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