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重組人甘露聚糖結合凝集素絲氨酸肽酶2蛋白

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產(chǎn)品編號bs-42117P
英文名稱Recombinant human MASP2 protein, N-His
中文名稱重組人甘露聚糖結合凝集素絲氨酸肽酶2蛋白
別    名mannan-binding lectin serine peptidase 2; MAP19; MASP-2; Mannose-binding protein-associated serine protease 2; MBL-associated serine protease 2; MASP1P1; sMAP; Small MBL associated protein.(Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain).  
理論分子量18.3kDa
性    狀Lyophilized or Liquid
濃    度1mg/ml
物    種Human
序    列428-575/686
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)E.coli
活性Not tested
標簽N-His
緩 沖 液20mM Tris-Hcl (pH=8.0) with 8M Urea
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]


SWISS:
O00187

Gene ID:
10747

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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