| 產品編號 | bs-43160P |
| 英文名稱 | Recombinant human HLA-B & Beta-2-MG Heterodimer protein, His&Avi (HEK293) |
| 中文名稱 | 重組人組織相容性復合體蛋白 |
| 別 名 | HLAB_HUMAN; HLA class I histocompatibility antigen, B alpha chain; Human leukocyte antigen B (HLA-B); HLAB; |
| 理論分子量 | 35.8kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >0.5mg/ml |
| 物 種 | Human |
| 純 度 | >90% as determined by SDS-PAGE |
| 內毒素 | Not analyzed |
| 表達系統 | HEK293 cell |
| 活性 | Not tested |
| 標簽 | C-His&Avi |
| 緩 沖 液 | PBS (pH=7.4) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008] SWISS: P01889 Gene ID: 3106 |
| 產品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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