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重組胞質(zhì)緊密粘連蛋白1

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產(chǎn)品編號(hào)bs-41327P
英文名稱Recombinant human ZO-1 protein, His
中文名稱重組胞質(zhì)緊密粘連蛋白1
別    名Na Cl symporter; Na-Cl symporter; NaCl electroneutral thiazide sensitive cotransporter; NCCT; S12A3_HUMAN; slc12a3; Solute carrier family 12 (sodium/chloride transporters) member 3; Solute carrier family 12 member 3; Thiazide sensitive Na Cl cotransporter; Thiazide sensitive sodium chloride cotransporter; Thiazide-sensitive sodium-chloride cotransporter; TSC; Recombinant human SLC12A3 protein, N-His Tag   
理論分子量33.2kDa
性    狀Lyophilized or Liquid
濃    度>0.5mg/ml
物    種Human
純    度>90% as determined by SDS-PAGE
表達(dá)系統(tǒng)E.coli
活性Not tested
標(biāo)簽N-His
緩 沖 液20mM Tris(pH=8.0)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

SWISS:
Q07157

Gene ID:
7082

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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