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重組人抑癌基因蛋白

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產(chǎn)品編號(hào)bs-42084P
英文名稱Recombinant human DMBT1 protein, C-His
中文名稱重組人抑癌基因蛋白
別    名GP340; Apactin; CRP; CRP-[a]; CRP-[b]; CRP-ductin; Crpd; DBMT1; Deleted in malignant brain tumors 1; Deleted in malignant brain tumors 1 protein; DMBT 1; DMBT1 prototype precursor; DMBT1/6kb.1 protein precursor; DMBT1/8kb.1 protein; DMBT1/8kb.2 protein precursor; Ebnerin; Glycoprotein 300; Glycoprotein 340; Gp 340; gp300; Gp340 variant protein; Hensin; Mucin-like glycoprotein; Muclin; p80; Pancrin; Salivary agglutinin; Surfactant pulmonary associated D binding protein; Surfactant pulmonary associated protein D binding protein; Vomeroglandin.  
理論分子量38.7kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
標(biāo)簽C-His
緩 沖 液20mM Tris-Hcl (pH=8.0) with 8M Urea
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹DMBT 1 may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular(oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophages tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. [Subcellular Location] Secreted. Membrane. [Tissue Specificity] Expressed in von Ebner glands (VEG) (at protein level), olfactory epithelium and the lateral nasal gland. Expressed in transit-amplifying ductular (oval) cells. Up-regulated at day 3 after hepatectomy. Expressed in newly formed bile ducts and in structures resembling intestinal epithelium. Belongs to the DMBT1 family.

SWISS:
Q9UGM3

Gene ID:
1755

DMBT1是分泌型的清道夫受體,富含半胱氨酸,主要在腸道表達(dá),參與再生和防御病原體的功能。 有學(xué)者認(rèn)為:DMBT1在消化系統(tǒng)的惡性腫瘤的發(fā)生、發(fā)展及轉(zhuǎn)移中起一定作用。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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