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突變型β淀粉樣肽1-40多肽

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產品編號Y-0113
英文名稱beta Amyloid 1-40 (mutation type, MT) Peptide
中文名稱突變型β淀粉樣肽1-40多肽
別    名beta Amyloid(1-40); beta Amyloid 1-40; beta-Amyloid 1-40; Amyloid 1-40; A Beta 1-40; A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid Beta A4 Protein Precursor; Amyloid Beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; Beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; A4_HUMAN.  
性    狀Lyophilized powder
序    列DAEFRd-HDSGYEVd-Hd-HQKLVFFAEDVGSNKGAIIGLMVGGVV(d-H6;d-H13;d-H14)
純化方法HPLC
活性Yes
保存條件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
產品介紹The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

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