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腎上腺髓質(zhì)素(22-52)多肽

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產(chǎn)品編號Y-0184
英文名稱Adrenomedullin(22-52) Peptide
中文名稱腎上腺髓質(zhì)素(22-52)多肽
別    名ADM; ADM precursor; ADML_HUMAN.  
性    狀Lyophilized powder
序    列TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2
純化方法HPLC
活性Yes
保存條件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

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