| 產(chǎn)品編號(hào) | bs-1223P |
| 英文名稱(chēng) | Aggrecan Antibody Blocking Peptide |
| 中文名稱(chēng) | 軟骨蛋白聚糖封閉多肽 |
| 別 名 | Aggrecan; Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1; Aggrecan core protein 2; AGC1; CSPG1; MSK16; PGCA_HUMAN. |
 | Specific References (2) | bs-1223P has been referenced in 2 publications. [IF=2.985] He D et al. Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell pyroptosis via NLRP3-dependent pathway. Biochem Biophys Res Commun. 2020 Jun 4;526(3):772-779. IHC ; rabbit. [IF=2.278] Ye W et al. Pulsed Electromagnetic Field Versus Whole Body Vibration on Cartilage and Subchondral Trabecular Bone in Mice With Knee Osteoarthritis. Bioelectromagnetics. 2020 May;41(4):298-307. IHC ; mouse. |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 | bs-1223P is one synthetic peptide derived from human ACAN. Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS. SWISS: P16112 Gene ID: 176 |
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