| 產品編號 | bs-2140P |
| 英文名稱 | IL17A Antibody Blocking Peptide |
| 中文名稱 | 白介素-17封閉多肽 |
| 別 名 | IL-17; IL 17; IL17; Other Aliases: Interleukin-17; CTLA 8 ; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8 ; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL17A; Interleukin 17; Interleukin 17A; Interleukin17; Interleukin17A; IL17_HUMAN. |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產品介紹 | bs-2140P is one synthetic peptide derived from human IL-17. IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17. SWISS: Q16552 Gene ID: 3605 |
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