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鈉離子/牛磺膽酸共轉運蛋白封閉多肽

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產品編號bs-1958P
英文名稱SLC10A1 Antibody Blocking Peptide
中文名稱鈉離子/牛磺膽酸共轉運蛋白封閉多肽
別    名Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN.  
性    狀Lyophilized powder
物    種human
純化方法HPLC
活性Not tested
保存條件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
產品介紹Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM]

SWISS:
Q14973

Gene ID:
6554

NTCP(鈉離子/牛磺膽酸共轉運蛋白)(鈉離子-牛磺膽酸共轉運多肽)Na+/taurocholate Cotransporting Polypeptide是肝臟的膽汁酸鹽吸收主要是鈉離子依賴性轉運子NTCP介導的,主要吸收牛磺膽酸,是肝細胞特有的一種轉運載體,分布在肝細胞基側膜在肝小葉和肝的腺泡表達較多。
有學者認為:NTCP是乙肝病毒的細胞表面受體分子,是HBV和HDV的功能受體,這些研究將有待于科研人員的進一步證實。
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