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腦腸肽封閉多肽

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產(chǎn)品編號(hào)bs-1375P
英文名稱(chēng)Ghrelin 28 Antibody Blocking Peptide
中文名稱(chēng)腦腸肽封閉多肽
別    名Appetite regulating hormone; Ghrelin 27; Ghrelin 28; Ghrelin/obestatin prepropeptide; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; Motilin related peptide; MTLRP; Obestatin; Obestatin preprohormone; PRO1066; UNQ524; GHRL_HUMAN.  
性    狀Lyophilized powder
物    種mouse
序    列GSSFLSPEHQKAQQRKESKKPPAKLQPR
純化方法HPLC
活性Yes
保存條件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]

SWISS:
Q9UBU3

Gene ID:
58991

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