| 產(chǎn)品編號 | bs-0563P |
| 英文名稱 | MDR1 Antibody Blocking Peptide |
| 中文名稱 | 多藥耐藥蛋白/P-糖蛋白封閉多肽 |
| 別 名 | P-Glycoprotein; Multi Drug Resistance Associated Protein, ABCB1; ATP-binding cassette sub-family B (MDR/TAP), member 1; ABC20; CD243; CD243 antigen; CLCS; Multidrug resistance protein 1; P glycoprotein 1; p-GP; gp170; P gp; PGY1; MDR1_HUMAN. |
 | Specific References (1) | bs-0563P has been referenced in 1 publications. [IF=3.115] Li Y et al. Paris saponin VII reverses chemoresistance in breast MCF-7/ADR cells.(2018) J Ethnopharmacol 232:47-54. ELISA ; |
| 性 狀 | Lyophilized powder |
| 物 種 | mouse |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 | P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas. SWISS: P21447 Gene ID: 5243 |
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