產品編號 | bs-0471P |
英文名稱 | ADIPOQ Antibody Blocking Peptide |
中文名稱 | 脂聯素封閉多肽 |
別 名 | 30 kDa adipocyte complement related protein; 30 kDa adipocyte complement-related protein; ACDC; ACRP 30; ACRP30; ADIPO_HUMAN; Adipocyte; Adipocyte C1q and collagen domain containing protein; Adipocyte complement related 30 kDa protein; Adipocyte complement related protein of 30 kDa; Adipocyte complement-related 30 kDa protein; Adiponectin; AdipoQ; Adipose most abundant gene transcript 1; Adipose most abundant gene transcript 1 protein; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM 1; apM-1; ApM1; C1q and collagen domain-containing protein; GBP 28; GBP28; Gelatin binding protein; Gelatin binding protein 28; Gelatin-binding protein. |
性 狀 | Lyophilized powder |
物 種 | human |
純化方法 | HPLC |
活性 | Not tested |
保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
產品介紹 | Adiponectin: A protein hormone produced and secreted exclusively by adipocytes (fat cells) that regulates the metabolism of lipids and glucose. Adiponectin influences the body's response to insulin. Adiponectin also has antiinflammatory effects on the cells lining the walls of blood vessels. High blood levels of adiponectin are associated with a reduced risk of heart attack. Low levels of adiponectin are found in people who are obese (and who are at increased risk of a heart attack). Adipocytes produce and secrete a number of proteins, including leptin, adipsin, properdin, and tumor necrosis factor (TNF). An adipose tissue-specific factor was isolated and termed APM1 (AdiPose Most abundant gene transcript 1). The protein product of APM1 is adiponectin. The APM1 gene maps to chromosome 3q27. SWISS: Q15848 Gene ID: 9370 脂聯素作為一種胰島素超敏化激素(An Insulin–sensitizing Hormone),可以增加促進骨骼肌細胞的脂肪酸氧化和糖吸收,明顯加強胰島素的糖元異生作用,抑制肝臟的糖生成,是機體的脂質代謝和血糖穩態的調控網絡中的重要調節因子,在脂肪細胞分泌的具有生物活性的一類蛋白質因子中脂聯素是脂肪組織基因表達最豐富的蛋白質產物之一,大量存在于血液循環中。在人體內以3-30ug/ml的濃度出現在循環血漿中。 |
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