| 產品編號 | Y-0492 |
| 英文名稱 | SAAP-148 peptide |
| 中文名稱 | SAAP-148抗菌肽 |
| 別 名 | P148; SAAP 148 |
| 理論分子量 | 3.268kDa |
| 性 狀 | Lyophilized powder |
| 序 列 | LKRVWKRVFKLLKRYWRQLKKPVR-NH2 |
| 純化方法 | HPLC |
| 活性 | Yes |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | SAAP 148 is a synthetic peptide derived from LL-37 which is more stable to plasma proteases and more effective in eradicating bacteria than the parent peptide. In vitro, SAAP (synthetic antimicrobial and antibiofilm peptide) 148 kills MDR pathogens without inducing resistance, prevents biofilm formation, and eliminates established biofilms and persister cells. A single 4-hour treatment with SAAP 148 completely eradicates acute and established biofilm associated infections with methicillin resistant Staphylococcus aureus and MDR Acinetobacter baumannii from wounded ex vivo human skin and murine skin in vivo |
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