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重組周期素依賴性激酶2蛋白

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產(chǎn)品編號bs-42064P
英文名稱Recombinant human CDK2 protein, C-His
中文名稱重組周期素依賴性激酶2蛋白
別    名Cdc2 related protein kinase; cdc2-related protein kinase; Cdk 2; CDK2_HUMAN; Cell devision kinase 2; Cell division kinase 2; Cell division protein kinase 2; Cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 2; p33 protein kinase; p33(CDK2).  
理論分子量24.1kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
序    列8-210/298
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
標(biāo)簽C-His
緩 沖 液20mM Tris-Hcl (pH=8.0) with 8M Urea,0.18M L-Arginine
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

SWISS:
P24941

Gene ID:
1017

Cdk2為周期素依賴激酶2(Cyclin-Dependent Kinase 2),主要參與細(xì)胞周期的調(diào)控,在細(xì)胞分化、有絲分裂中起重要作用,目前主要用于各種腫瘤的研究。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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