| 產品編號 | bs-42207P |
| 英文名稱 | Recombinant mouse ABCA12 protein, N-His |
| 中文名稱 | 重組小鼠腺苷三磷酸結合盒轉運體12蛋白 |
| 別 名 | ABC transporter A family member 12; ABC transporter ABCA.12; ABC12; ABCA12; ABCAC_HUMAN; AtABCA12; ATH16; ATP binding cassette 12; ATP binding cassette sub family A (ABC1) member 12; ATP binding cassette sub family A member 12; ATP binding cassette transporter 12; ATP-binding cassette 12; ATP-binding cassette sub-family A member 12; ATP-binding cassette transporter 12; Ichthyosis congenita II lamellar ichthyosis B; ICR2B; LI2; Putative ABC2 homolog 16; ABCAC_MOUSE. |
| 理論分子量 | 26.1kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >0.5mg/ml |
| 物 種 | Mouse |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內毒素 | Not analyzed |
| 表達系統 | E.coli |
| 標簽 | N-His |
| 緩 沖 液 | 20mM Tris-HCL (pH=7.4) with 8M Urea |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | The ATP-binding cassette (ABC) transporters, or traffic ATPases, constitute an expansive family of proteins accountable for the transport of a wide variety of substrates across cell membranes in both prokaryotic and eukaryotic cells. They also aid in the regulation of lipid transport and membrane trafficking. ABCA12 (ATP-Binding Cassette, Subfamily A, Member 12) contains two transmembrane (TM) domains, each with six membrane-spanning segments, and two nucleotide-binding domains (NBDs), which are located in the cytoplasm. ABCA12 is expressed in normal human keratinocytes (RT-PCR reveals expression in placenta, testis, fetal brain, and skin) and is upregulated during keratinization. Immunoelectron microscopy reveals that the ABCA12 protein is located in lamellar granules in the upper epidermal keratinocytes of human skin. The ABCA12 gene, which synthesizes a 2,595-amino acid protein, may produce an alternative splice variant with an in-frame deletion leading to truncation of 79 amino acids. SWISS: E9Q876 Gene ID: 74591 |
| 產品圖片 |  The purity of the protein is greater than 85% as determined by reducing SDS-PAGE. |
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