| 產品編號 | bs-42187P |
| 英文名稱 | Recombinant human FIBIN protein, N-Trx-His |
| 中文名稱 | 重組人FIBIN蛋白 |
| 別 名 | Fibin; FIBIN_HUMAN; Fin bud initiation factor homolog (zebrafish); Fin bud initiation factor homolog; MGC24932; PSEC0235. |
| 理論分子量 | 40.1kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >1mg/ml |
| 物 種 | Human |
| 序 列 | 19-211/211 |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 表達系統 | E.coli |
| 活性 | Not analyzed |
| 標簽 | N-Trx-His |
| 緩 沖 液 | 20mM Tris-Hcl (pH=8.0) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | FIBIN (Fin bud initiation factor homolog) is a 211 amino acid protein involved in fin initiation in zebrafish. The human homolog is encoded by a gene that maps to chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. |
| 產品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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