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重組人IL18蛋白

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產品編號bs-42309P
英文名稱Recombinant human IL-18 protein
中文名稱重組人IL18蛋白
別    名Interleukin-18; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL-18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; Interferon gamma inducing factor; Interleukin 1 gamma; Interleukin18; MGC12320; IL18_HUMAN  
理論分子量18.2kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
序    列37-193/193
純    度>90% as determined by SDS-PAGE
純化方法AC
內毒素Not analyzed
表達系統E.coli
標簽Tag Free
緩 沖 液20mM Tris-Hcl (pH=8.0) with 2M Urea
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.

SWISS:
P97636

Gene ID:
29197

IL-18是巨噬細胞分泌的一個重要因子,它具有多種免疫功能,能誘導產生IFNγ,無論在病毒感染早期或特異性細胞免疫應答效應階段都會出現,因此IL-18主要參與免疫應答及炎性細胞浸潤的改變。Interleukin-18 又稱inteferon-gamma inducing factor(IGIF),在輔助T細胞的應答反應中起重要作用。IL-18和IL-1一起,既參與先天免疫,又是后天免疫的構成因素。
產品圖片
The purity of the protein is greater than 80% as determined by reducing SDS-PAGE.
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