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重組小鼠 FCGRT & B2M Heterodimer 蛋白

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產品編號bs-43206P
英文名稱Recombinant mouse FCGRT&B2M Heterodimer protein, C-His (HEK293)
中文名稱重組小鼠 FCGRT & B2M Heterodimer 蛋白
理論分子量33kDa
性    狀Lyophilized or Liquid
濃    度>0.5mg/ml
物    種Mouse
純    度>90% as determined by SDS-PAGE
內毒素Not analyzed
表達系統HEK293 cell
標簽C-His
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn ? chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.

SWISS:
P55899

Gene ID:
2217

產品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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