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重組人谷氨酰胺合成酶蛋白

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產品編號bs-42310P
英文名稱Recombinant human Glutamine synthetase protein, N-His
中文名稱重組人谷氨酰胺合成酶蛋白
別    名GLUL; cell proliferation-inducing protein 59; GLNA; GLNA_HUMAN; GLNS; Glutamate ammonia ligase; Glutamate decarboxylase; Glutamate--ammonia ligase; glutamine synthase; GS; PIG 43; PIG 59; PIG43; PIG59; Proliferation inducing protein 43.  
理論分子量45.6kDa
性    狀Lyophilized or Liquid
濃    度>0.5mg/ml
物    種Human
序    列1-373/373
純    度>90% as determined by SDS-PAGE
純化方法AC
內毒素Not analyzed
表達系統E.coli
標簽C-His
緩 沖 液20mM Tris-Hcl (pH=8.0) with 150mM Nacl
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.

SWISS:
P15104

Gene ID:
2752

產品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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