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微管相關蛋白Tau-4單克隆抗體

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產品編號V5213
英文名稱Human Tau
中文名稱微管相關蛋白Tau-4單克隆抗體
別    名MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; 2N4R; microtubule-associated protein tau isoform 2; Isoform Tau-F;TAU_HUMAN.   
克 隆 號7A2
理論分子量46/79kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
緩 沖 液0.01M PBS(pH7.4)
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

SWISS:
P10636-8

Gene ID:
4137

Database links:

Entrez Gene: 281296 Cow

Entrez Gene: 4137 Human

Entrez Gene: 17762 Mouse

Entrez Gene: 29477 Rat

Omim: 157140 Human

SwissProt: P29172 Cow

SwissProt: P10636 Human

SwissProt: P10637 Mouse

SwissProt: P19332 Rat

Unigene: 101174 Human

Unigene: 1287 Mouse

Unigene: 2455 Rat  



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